Introduction

The polypill as an alternative for preventing and treating cardiovascular disease

Globally, cardiovascular disease (CVD) remains the most important cause of death and a common cause of disability. While the burden of CVD has slightly decreased in high-income countries, it remains disproportionately higher in low- to middle income countries. Ischemic heart disease and stroke are the leading contributors of CVD. Several risk factors contribute to increased risks of CVD, including hypertension, elevated LDL cholesterol, high blood sugar, and behavioural factors such as physical inactivity, smoking, poor diet and obesity.

Gout

Gout is an inflammatory arthritis that can be monoarticular or polyarticular. It manifests as an acute, sub-acute or chronic condition and often mimics other medical diseases. It can evolve over time, both in frequency, severity and involved sites. It can co-exist with other medical problems and can be difficult to treat. However, gout is often poorly treated, and patients are often poorly educated about the disease process. As a result, patients often have significant impairment in their quality of life and are at risk from complications due to excess use of anti-inflammatories in an attempt to quell their pain.

Menopause and MHT in 2024: addressing the key controversies – an International Menopause Society White Paper

The aim of this 2024 White Paper is to provide an International Menopause Society (IMS) position statement about menopause and menopause hormone therapy (MHT), and in particular to address some of the key controversies. The paper’s purpose is to act as a blueprint upon which to base the future ethical management of menopause from both practical and aspirational perspectives.

What is mpox? A microbiologist explains what’s known about this smallpox Cousin

Mpox – previously called monkeypox – isn’t a new disease. The first confirmed human case was in 1970, when the virus was isolated from a child suspected of having smallpox in the Democratic Republic of Congo (DRC). Though usually mild, mpox can still potentially cause severe illness. Health officials are concerned that more cases will arise with increased travel.


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South African General Practitioner - 2024 Vol 5 No 3